PANS & PANDAS: Do symptoms always come on abruptly?
Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS) is a clinical diagnosis given to children who have a dramatic - sometimes overnight - onset of neuropsychiatric symptoms. These symptoms often include obsessive-compulsive behaviors, severe restrictions in eating, and anxiety.
The word "acute" in PANS indeed refers to the sudden onset of symptoms. But, as with most illnesses, the answer is more complex than that. Continue reading to learn more.
While the "acute onset" is a hallmark of PANS, it's essential to understand that the presentation of symptoms can vary greatly among individuals, and not all cases have such an abrupt start.
In some children, the onset of symptoms may appear more insidious or gradual rather than a clear-cut sudden onset. There may be mild or vague symptoms that precede the more significant, noticeable symptoms, which can lead to confusion or delays in diagnosis. This can happen because the child's symptoms might not meet the "classic" definition of PANS.
Additionally, after the initial acute onset, children with PANS may experience fluctuations in the intensity of their symptoms. These fluctuations can occur in response to various triggers, like infections, stress, or changes in routine. The symptoms might subside and then re-emerge, which might give the impression of a non-acute or ongoing progression.
As a result, while the term PANS implies an acute onset, clinicians, patients, and families should be aware that the disease course can be variable and that symptoms might not always appear suddenly or intensively. As with any complex condition, it's crucial to monitor symptoms closely and seek professional healthcare advice when necessary.
